The Prescription: 1st August 2016 Issue
Editor’s EmulsionPSM INDIA Capsules Drug Laws & Policy Injections Pharma Injections DRUG DOPES National Injections Global Injections PSM Pill DOSE OF THE DAY FAQ Subscriber's Symptom UpComing Events Laughter Dose Blog Addict Contact Us
News Archive
EDITOR'S EMULSION

Pooja Khaitan

Greetings!

Each year, approximately 700,000 people die from drug-resistant bacterial infections around the world. Scientists have achieved a step toward combating drug-resistant infections, what has become a major public health risk today. However, we need a stringent policy to stop the overuse of antibiotics; something we have regularly briefed our readers and continue doing so.

Inauguration of Maa Medicine Bank in Maa Anandamayi Hospital, Varanasi has added one more feather in our hat as this novel initiative has been taken by our foundation ‘Patient Safety and Access Initiative Foundation of India’ and Medlife in order to provide cheap medical facilities to every citizen. Read more on this in PSM India Capsules. Read More>>>

If you have any suggestions, comments or queries, please email me at pooja@safemedicinesindia.in.
You may find our previous issues on www.safemedicinesindia.in or in the NEWS ARCHIVE section of every issue of The PRESCRIPTION, in case you’ve missed any of them. You may also look us up on Facebook under Partnership for Safe Medicines India

"Call PSM India toll free helpline 1800 - 11- 4424, to bring cases of spurious medicines or any kind of adverse drug reaction to the notice of the authorities.
Please visit our website www.safemedicinesindia.in if you wish to learn about us .
To register a complaint kindly visit our consumer redressal website www.consumerconexion.org

Happy Reading !
Stay Safe. Stay Healthy !

Pooja Khaitan
Chief Editor , The PRESCRIPTION Partnership for Safe Medicines India.

DOSE OF THE DAY

"We are committed to promoting the use of traditional medicine in our public health system through regulation of research and appropriate integration of quality products, practices and practitioners into the health system,"

Narendra Modi
Prime Minister of India

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PSM India Capsules

Another feather in our hat - MAA Anandamayi Medicine Bank inaugurated

The novel pilot project, ‘MAA's MEDICINE BANK’, initiated by the Patient Safety and Access Initiative Foundation of India at Maa Anandamayi Hospital, Shivalaya, Varanasi on 14th July 2016 is another leading step in the Universal Health Coverage Project after the successful launch of the JAN AUSHADHI Store on 1st January 2016 to provide better medical facilities to the every citizen, especially the poor who need it most.

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Combating drug-resistant bacterial infections

Every year, around 700,000 people die from drug-resistant bacterial infections. A recent study by UCLA life scientists could be a major step toward combating drug-resistant infections.
The study found that combinations of three different antibiotics can overcome bacteria's resistance to antibiotics, even when none of the three antibiotics on their own--even two of the three together--is effective. The scientists grew E. Coli bacteria in a laboratory and treated the samples with combinations of one, two and three antibiotics from a group of 14 drugs. The biologists studied how effectively every single possible combination of drugs worked to kill the bacteria.

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Drug Laws & Policy Injections
Act for medical devicesNew Delhi, July’16: The Union ministry of health announced last week that a Medical Device Act would be tabled in the winter session of the Parliament. The announcement came from the minister of health while taking part in a consultation convened by the Prime Minister’s Office for promoting Make in India initiative in the medical devices sector. Read More
Govt. may introduce iris scans for nod to organ transplants Mumbai July’16 : The state is planning to take a cue from the implementation of the PCPNDT Act (which is aimed at checking female foeticide) in order to control the illegal trade in human organs. Besides introducing iris scanners and linking transplant paperwork to Aadhar cards, the state will launch an information campaign highlighting that organ trade is illegal and can attract imprisonment and fines of up to Rs 1 crore.Read More
Coronary Stents set to come under price control, government brings it under NLEMMumbai, July 2016: Stents look set to come under price control following a Union Health Ministry notification to include it in the National List of Essential Medicines (2015). While the move brings some cheer to patients, an uneasy calm prevails over sections of the medical device industry, following the Ministry’s communication late on Tuesday. Read More
DoP agrees to AIOCD's demand for allowing sale of drugs at pre-revised prices until their batch number expiresMumbai, July 2016: The Department of Pharmaceuticals (DoP) has agreed in-principle to All India Organization of Chemists and Druggists (AIOCD)'s demand for allowing sale of medicines, whose ceiling prices have been revised by NPPA, at their pre-revised prices until their batch number expires. Read More
No permission given to hike drug prices beyond limitsNew Delhi, July 2016: Government has not given nod to any pharma firm to increase prices of drugs beyond permissible limits, Parliament was informed today. Read More
Modi Cabinet Okays AIIMS at GorakhpurNew Delhi, July 2016: For providing quality health care services in eastern UP and western Bihar, the Union Cabinet has approved a new 750-bedded All India Institute of Medical Sciences (AIIMS) in Gorakhpur at an estimated cost of Rs 1011 crore. Read More
Pharma Injections
Sanofi-Synthelabo India launches 2 diabetes drugsNew Delhi, July’16: Drug firm Sanofi-Synthelabo India has expanded Sanofi's diabetes portfolio in the country with launch of two drugs - Lyxumia and Zemiglo - for lowering blood sugar levels. Read More
Fortis Healthcare dedicates 'Wall of tribute' to organ donorsNew Delhi, July 2016: The Fortis Escorts Heart Institute (FEHI), New Delhi, has dedicated a 'Wall of Tribute' to organ donors and their families who helped save lives. Read More
Fluctuations in bad cholesterol may lead to memory loss July’16: Greater fluctuations in "bad" cholesterol levels are likely to cause worse cognitive function like acute memory loss in elderly adults, says a research. Read More
Kerala government to launch e-health card for each person with detailed health data for future treatment Chennai, July’16: Aimed to completely revamp the state’s health sector, a first of its kind health project, e-health programme, will be implementing in Kerala by the state government shortly. The programme will consist of introducing Electronic Health Card for each person with coverage of comprehensive data about his health status. Read More
Drug Dopes
Updated LIST OF NEW DRUG APPROVED FROM 01-01-2016 to TILL DATE BY NEW DRUGS DIVISION, CDSCO, FDA Bhawan, New Delhi List of New Drug Approved by FDA Read More
Five diabetes drugs in top-10 selling list MUMBAI, 21 JULY 2016: In perhaps a grim reminder of the growing incidence of lifestyle diseases, five out of the top 10 largest-selling drugs in the country are now anti-diabetes, with the therapy registering a robust double-digit clip year-on-year. Read More
660 Pharma Companies have registered with IPDMS till date New Delhi, July 2016: A total of 660 pharmaceutical companies have registered with the government's pharma data bank till date and 58,027 product details have been entered in the system, Parliament was informed today. Read More
US FDA approves new expanded label for Namzaric XR to treat moderate to severe Alzheimer's disease Dublin, July 2016: Allergan plc, a global pharmaceutical company, and Adamas Pharmaceuticals, Inc. announced that the US Food and Drug Administration (FDA) has approved a new, expanded label for Namzaric (memantine and donepezil hydrochlorides) extended-release, a once-daily, fixed-dose combination of memantine hydrochloride (a NMDA receptor antagonist) and donepezil hydrochloride (an acetylcholinesterase inhibitor, AChEI). Read More
Drug-makers in race to make smart inhalers London, July 2016 : Makers of inhalers to treat asthma and chronic lung disease are racing to develop a new generation of smart devices with sensors to monitor if patients are using their puffers properly. Read More
New drug found to block Zika virus' journey from mum to her fetus JULY, 2016: Looks like a way out has been found to prevent Zika virus to travel from a pregnant woman to her fetus.
Zika virus can infect numerous cell types in the human placenta and amniotic sac, according to researchers at UC San Francisco and UC Berkeley. They also identify a drug that may be able to block it.The virus has two potential routes to the developing fetus: a placental route established in the first trimester, and a route across the amniotic sac that only becomes available in the second trimester, according to the study.
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Taking anti-HIV pill as needed prevents infection Reuters, JULY’16: Taking an anti-HIV pill shortly before sex and for a few days afterward can help protect people against infection with the human immunodeficiency virus, according to researchers in France and Canada. Read More
National Injections
Four out of 5 India's rural 'doctors' are quacks: WHO New Delhi, July 2016: Only one in five doctors in rural India are qualified to practice medicine, says a World Health Organization report on India's healthcare workforce, pointing to the widespread problem of quackery.
The report, 'The Health Workforce in India', based on 2001 census data and published in June, also says nearly one-third of those calling themselves allopathic doctors were educated only up to Class 12. Also, 57 percent of the practitioners did not have any medical qualification.
Read More
Tragedy in Hyderabad hospital: 21 patients die within hours Hyderabad July, 2016 : In a tragic incident, 21 patients died at a government hospital within a matter of hours in Hyderabad on Friday, July 22. Shockingly, the hospital staff blamed power cut for the deaths. Read More
Maharashtra woman moves Supreme Court to abort abnormal 24-week-old fetus New Delhi, July 2016: The Supreme Court on Thursday sought the response of the Centre and Maharashtra government within 24 hours over a rape survivor's distress plea to abort her 24-week pregnancy citing serious abnormalities with the fetus. Read More
Five new diphtheria cases reported in Malappuram MALAPPURAM, July 2016: Even as vaccination and awareness drives against diphtheria continue in full swing in the district, five new cases of the disease were reported on Thursday. Read More
Eye surgery botch up: Victims to get 3 lakh Chennai, July 2016: Tamil Nadu chief minister J Jayalalithaa on Sunday sanctioned Rs3 lakh each to 23 people who developed eye infection after undergoing cataract surgeries at the Mettur Government Hospital last month. Read More
Child dies in hospital, kin attack 3 junior docs New Delhi,, July 2016: At least three junior resident doctors were assaulted by a patient's attendant at Kalawati Saran Children's Hospital on Thursday, leading to protests and strike at work by doctors. Read More
Global Injections
WHO flags four challenges for global HIV response July’16: With an aim to enhance its efforts to end AIDS, the World Health Organization (WHO) has flagged four key challenges - prevention, treatment, drug resistance and financing - for a sustainable response, as the international community meets at the International AIDS Conference in Durban, South Africa, from 18-22 July, 2016. Read More
Soon, a 'needle-free' vaccine for STI Chlamydia July’16:Washington D.C, July 2016: World's first vaccine for an insidious sexually transmitted infection (STI) has come closer to reality in the form of a nose spray. Researchers at the Michael G. DeGroote Institute for Infectious Disease Research at McMaster have developed the first widely protective vaccine against chlamydia, Read More

Menopause reversed, women could now stay fertile foreverAthens, July 2016: Scientists have announced they can now reverse the menopause in what is thought to be a major scientific breakthrough. Trials claim to have "rejuvenated" women's ovaries using a blood treatment normally used to help wounds heal faster, and have reversed menstrual cessation in multiple women, including a 40-year-old who underwent the menopause five years ago.Read More

CDC probes possible first homegrown case of Zika in U.S.MIAMI, July 2016: Health officials in Florida are investigating what could be the first Zika infection from a mosquito bite in the continental United States, involving a resident of the Miami area.Read More

Breastfeeding may reduce mother's risk of diabetesJuly 2016: Breastfeeding has the potential to reduce the long-term risk of developing Type 2 diabetes among women with gestational diabetes, and is a cost-effective intervention, says a study.Read More

PSM PILL

Women in 2 states indicted in separate clandestine silicone injection scams

In May, both Maryland and Florida prosecuted 2 women for injecting unsuspecting patients with industrial-grade silicone. The Florida case resulted in a death.

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Connecticut senator calls for state medical board intervention in cases where doctors bought misbranded drugs from gallant pharma

Although 5 doctors in Connecticut and 256 doctors nationwide have received FDA warning letters concerning purchases of non-FDA approved medication from the now-defunct medicine wholesaler Gallant Pharma International, no state medical boards have investigated any of their practices. Now Senator Richard Blumenthal of Connecticut is calling for the FDA to provide these names to state medical boards for enforcement.

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Frequently Asked Questions Q1. What is the Urea Cycle?
Answer: In humans and mammals, almost 80% of the nitrogen is excreted in the form of urea, which is produced through a series of reactions occurring in the cytosol and mitochondrial matrix of liver cells. These reactions are collectively called the urea cycle or the Krebs-Henseleit cycle.
Ammonia is a toxic product of nitrogen metabolism, which should be removed from our body. The urea cycle or ornithine cycle converts excess ammonia into urea in the mitochondria of liver cells. The urea forms, then enters the blood stream, is filtered by the kidneys and is ultimately excreted in the urine.
The overall reaction for urea formation from ammonia is as follows:
2 Ammonia + CO2 + 3ATP ---> urea + water + 3 ADP Read More>>>

Q3. Significance of the Urea Cycle
Answer: The main purpose of the urea cycle is to eliminate toxic ammonia from the body. About 10 to 20 g of ammonia is removed from the body of a healthy adult every day. A dysfunctional urea cycle would mean the excess amount of ammonia in the body, which can lead to hyperammonemia and related diseases. The deficiency of one or more of the key enzymes catalyzing various reactions in the urea cycle can cause disorders related to the cycle. Defects in the urea cycle can cause vomiting, coma and convulsions in newborn babies. This is often misdiagnosed as septicemia and treated with antibiotics in vain. Even 1mm of excess ammonia can cause severe and irreversible damages. Read More>>>

SUBSCRIBER'S SYMPTOM

No juice, only water while consuming pills

Article contributed by one of our Subscriber: Anju Mariam, Coimbatore

Taking pills with fruit juices, particularly of citrus ones, can affect absorption in two ways....one, by the changing blood PH —acidity or alkalinity of the blood—and, two, by breaking the coating of the pills that makes the medicine less effective. Orange and apple juices have been shown to lower the absorption of certain drugs, thus compromising their effectiveness. On the other hand, grapefruit juice increases the absorption of some drugs. Read More

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